TESK1

Across TCGA patient cohorts, TESK1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,302 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TESK1-associated genes across cancer lineages are TBC1D23, SMU1, and TAGLN3. Each is linked with TESK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TESK1-to-partner and partner-to-TESK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TESK1 versus TBC1D23 in HNSC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TESK1→partner) and Y-score (partner→TESK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TBC1D23 →	+0.517	+0.922	.005	.002	3	2
LUAD	SMU1 →	+0.309	+0.257	<.001	.007	3	2
GBM	TAGLN3 →	+1.158	+0.233	.005	.002	3	2
LUAD	TOPORS →	+0.329	+0.231	.001	.006	3	2
LSCC	BAG1 →	+0.744	+0.369	<.001	.001	3	2
GBM	HIVEP2 →	+0.502	+0.279	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,302 associations by consensus.

TESK1 vs TBC1D23 — HNSC

Explore this scatter interactively →