TERT

Across TCGA cell cohorts, TERT RNA expression is significantly associated with the RNA expression of many other genes, with 9,470 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TERT-associated genes across cancer lineages are FANCA, MYBBP1A, and ATAD3B. Each is linked with TERT in more than 11 cancer types. Because this analysis shows association rather than direction, both TERT-to-partner and partner-to-TERT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TERT versus FANCA in BONE, with a Pearson correlation of 0.61.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TERT→partner) and Y-score (partner→TERT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	FANCA →	+1.679	+1.944	<.001	<.001	3	12
BLOOD_Lymphoma	MYBBP1A →	+1.271	+2.025	<.001	<.001	3	12
BONE	ATAD3B →	+1.573	+1.826	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	POLE →	+1.533	+1.229	<.001	<.001	3	11
BONE	PFAS →	+1.511	+2.077	.003	<.001	2	12
LARGE_INTESTINE	KLHDC4 →	+0.830	+0.956	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,470 associations by consensus.

TERT vs FANCA — BONE

Explore this scatter interactively →