TERF2

Across TCGA patient cohorts, TERF2 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TERF2-associated genes across cancer lineages are Osteoblast, Adipocytes, and MEP. Each is linked with TERF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TERF2-to-partner and partner-to-TERF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast grouped by TERF2-low versus TERF2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TERF2→partner) and Y-score (partner→TERF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Osteoblast →	+0.042	+2.606	.045	.006	3	2
UCEC	Adipocytes →	+0.017	+2.337	.037	.010	3	1
UCEC	MEP →	+0.039	+2.595	.002	.006	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Osteoblast by TERF2 expression — UCEC

Explore this box plot interactively →