TERF2

Across TCGA cell cohorts, TERF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,238 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TERF2-associated GO terms across cancer lineages are Nuclear transport, Nucleocytoplasmic transport, and mRNA alternative polyadenylation. Each is linked with TERF2 in more than 14 cancer types. Because this analysis shows association rather than direction, both TERF2-to-partner and partner-to-TERF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by TERF2-low versus TERF2-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TERF2→partner) and Y-score (partner→TERF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Nuclear transport →	+0.063	+0.863	<.001	.001	3	15
KIDNEY	Nucleocytoplasmic transport →	+0.064	+0.965	<.001	<.001	3	15
BONE	mRNA alternative polyadenylation →	+0.080	+0.596	<.001	<.001	3	14
SKIN	snRNA processing →	+0.073	+0.551	<.001	<.001	3	14
BREAST	Regulation of chromosome organization →	+0.071	+0.681	.004	.002	3	14
BLOOD_Lymphoma	Nucleic acid transport →	+0.089	+1.141	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,238 associations by consensus.

Nuclear transport by TERF2 expression — KIDNEY

Explore this box plot interactively →