TERF1

Across TCGA patient cohorts, TERF1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,913 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TERF1-associated genes across cancer lineages are TBC1D8B, SEC31A, and ARPC2. Each is linked with TERF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both TERF1-to-partner and partner-to-TERF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TERF1 versus TBC1D8B in LSCC, with a Pearson correlation of -0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TERF1→partner) and Y-score (partner→TERF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TBC1D8B →	-0.568	-0.206	<.001	.003	3	3
BRCA	SEC31A →	-0.354	-0.341	.001	.001	3	3
LSCC	ARPC2 →	-0.398	-0.357	<.001	<.001	3	3
LUAD	CPP →	-0.680	-0.142	<.001	.005	3	3
GBM	ACTG1P24 →	+0.324	+0.317	.005	.001	3	3
BRCA	KAT2A →	+0.711	+0.326	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,913 associations by consensus.

TERF1 vs TBC1D8B — LSCC

Explore this scatter interactively →