TERB2

Across TCGA patient cohorts, TERB2 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TERB2-associated genes across cancer lineages are IGFBP2, VHL, and Di-Ras3. Each is linked with TERB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TERB2-to-partner and partner-to-TERB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGFBP2 grouped by TERB2-low versus TERB2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TERB2→partner) and Y-score (partner→TERB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGFBP2 →	-0.971	-3.000	.004	.036	3	1
UCEC	VHL →	-0.987	-3.000	.005	.036	3	1
UCEC	Di-Ras3 →	-0.177	-3.000	.023	.036	3	1
UCEC	GATA6 →	-0.244	-3.000	.002	.035	2	1
UCEC	ATM →	-0.683	-3.321	.004	.010	1	2

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

IGFBP2 by TERB2 expression — UCEC

Explore this box plot interactively →