TEPSIN

Across TCGA cell cohorts, TEPSIN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,910 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TEPSIN-associated GO terms across cancer lineages are Negative regulation of transcription elongation by RNA polymerase II, Pre-mRNA catabolic process, and mRNA splice site recognition. Each is linked with TEPSIN in more than 17 cancer types. Because this analysis shows association rather than direction, both TEPSIN-to-partner and partner-to-TEPSIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of transcription elongation by RNA polymerase II grouped by TEPSIN-low versus TEPSIN-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEPSIN→partner) and Y-score (partner→TEPSIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of transcription elongation by RNA polymerase II →	+0.113	+0.981	<.001	.002	3	18
BONE	Pre-mRNA catabolic process →	+0.218	+0.967	<.001	<.001	3	18
OESOPHAGUS	mRNA splice site recognition →	+0.182	+1.350	<.001	<.001	3	18
CNS	Negative regulation of DNA-templated transcription, elongation →	+0.118	+0.965	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.119	-1.109	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.123	-1.169	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,910 associations by consensus.

Negative regulation of transcription elongation by RNA polymerase II by TEPSIN expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →