TENT5A

Across TCGA patient cohorts, TENT5A mutation is significantly associated with the RNA expression of many other genes, with 5,400 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TENT5A-associated genes across cancer lineages are RNU6-1213P, RNA5SP412, and PSAT1P4. Each is linked with TENT5A in more than 3 cancer types. Because this analysis shows association rather than direction, both TENT5A-to-partner and partner-to-TENT5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by TENT5A-low versus TENT5A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT5A→partner) and Y-score (partner→TENT5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-1213P →	+0.124	+2.877	<.001	.001	3	4
UCEC	RNA5SP412 →	+0.535	+2.143	<.001	<.001	3	3
LIHC	PSAT1P4 →	+0.083	+5.066	<.001	.001	3	3
UCEC	RPS10P21 →	+0.159	+1.550	.001	.002	3	3
UCEC	RNA5SP415 →	+0.389	+1.903	<.001	.001	3	3
CESC	IL21 →	+0.230	+3.405	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,400 associations by consensus.

RNU6-1213P by TENT5A expression — UCEC

Explore this box plot interactively →