TENT5A

Across TCGA cell cohorts, TENT5A mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TENT5A-associated genes across cancer lineages are CFHR2, RHOV, and AGXT2. Each is linked with TENT5A in more than 2 cancer types. Because this analysis shows association rather than direction, both TENT5A-to-partner and partner-to-TENT5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CFHR2 grouped by TENT5A-low versus TENT5A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT5A→partner) and Y-score (partner→TENT5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CFHR2 →	+0.135	+3.539	<.001	.002	3	3
BLOOD_Leukemia	RHOV →	+1.704	+3.115	<.001	.009	3	1
BLOOD_Leukemia	AGXT2 →	+0.002	+3.762	<.001	.007	3	1
BLOOD_Leukemia	FHOD3 →	+1.321	+3.328	.007	.009	3	1
BLOOD_Leukemia	FAM71F1 →	+0.148	+4.058	.001	.001	3	1
BLOOD_Leukemia	KAAG1 →	+0.055	+2.855	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

CFHR2 by TENT5A expression — BLOOD_Leukemia

Explore this box plot interactively →