TENT2

Across TCGA cell cohorts, TENT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,277 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TENT2-associated GO terms across cancer lineages are Target-directed miRNA degradation, Protein localization to vacuole, and Establishment of protein localization to vacuole. Each is linked with TENT2 in more than 18 cancer types. Because this analysis shows association rather than direction, both TENT2-to-partner and partner-to-TENT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Target-directed miRNA degradation grouped by TENT2-low versus TENT2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TENT2→partner) and Y-score (partner→TENT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Target-directed miRNA degradation →	+0.164	+0.699	<.001	.003	3	19
OESOPHAGUS	Protein localization to vacuole →	+0.076	+0.633	.005	<.001	3	16
OESOPHAGUS	Establishment of protein localization to vacuole →	+0.098	+0.630	<.001	.003	3	16
OESOPHAGUS	Protein targeting to vacuole →	+0.109	+0.638	.001	.002	2	16
LUNG_NSCLC_LUSC	Macroautophagy →	+0.058	+0.587	.001	.008	2	16
SKIN	Negative regulation of post-transcriptional gene silencing →	+0.151	+0.511	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,277 associations by consensus.

Target-directed miRNA degradation by TENT2 expression — PANCREAS

Explore this box plot interactively →