Across TCGA patient cohorts, TENM3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,317 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TENM3-associated genes across cancer lineages are RNU2-34P, TENM3-AS1, and MIR1305. Each is linked with TENM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TENM3-to-partner and partner-to-TENM3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENM3→partner) and Y-score (partner→TENM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RNU2-34P →	+1.393	+0.462	<.001	<.001	3	5
GBM	TENM3-AS1 →	+0.945	+0.527	<.001	<.001	3	4
HNSC	MIR1305 →	+2.105	+0.539	<.001	<.001	3	4
GBM	RN7SKP67 →	+1.014	+0.657	<.001	<.001	3	4
OV	PMP22 →	+1.050	+0.743	<.001	<.001	3	3
OV	DCN →	+1.385	+0.615	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,317 associations by consensus.

Exploration

TENM3 survival (RNA) · tumor vs normal (RNA) · all TENM3 data types