TENM1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TENM1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,470 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TENM1-associated genes across cancer lineages are SOX13, METTL27, and MYO5A. Each is linked with TENM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TENM1-to-partner and partner-to-TENM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TENM1 versus SOX13 in HNSC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENM1→partner) and Y-score (partner→TENM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCSOX13 →-0.981-0.465.004.00932
HNSCMETTL27 →-0.936-0.462<.001.00432
HNSCMYO5A →+0.547+0.439.003.00232
GBMMFNG →-0.672-0.584<.001<.00131
GBMSEZ6L →+1.091+0.543.004<.00131
GBMTSPO →-0.524-0.489.004.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,470 associations by consensus.

TENM1 vs SOX13 — HNSC

Per-sample scatter of TENM1 vs SOX13 in HNSC (Pearson r = -0.31).

Explore this scatter interactively →

Exploration