TENM1

Across TCGA cell cohorts, TENM1 mutation is significantly associated with the RNA expression of many other genes, with 1,828 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TENM1-associated genes across cancer lineages are C14orf178, GAGE12J, and CEACAM20. Each is linked with TENM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TENM1-to-partner and partner-to-TENM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C14orf178 grouped by TENM1-low versus TENM1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TENM1→partner) and Y-score (partner→TENM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C14orf178 →	+0.138	+3.020	<.001	.002	3	2
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	2
LUNG_SCLC	CEACAM20 →	+0.156	+2.350	.001	.004	3	2
CNS	CYP2A13 →	+0.019	+2.611	<.001	.001	3	2
BLOOD_Lymphoma	OR11H2 →	+0.023	+3.927	<.001	.004	3	2
CNS	ADGRG6 →	+1.663	+2.510	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,828 associations by consensus.

C14orf178 by TENM1 expression — BLOOD_Leukemia

Explore this box plot interactively →