TEKT5

Across TCGA patient cohorts, TEKT5 mutation is significantly associated with the RNA expression of many other genes, with 1,457 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEKT5-associated genes across cancer lineages are HMG20B, FBXL15, and RNU6-598P. Each is linked with TEKT5 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEKT5-to-partner and partner-to-TEKT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HMG20B grouped by TEKT5-low versus TEKT5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT5→partner) and Y-score (partner→TEKT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HMG20B →	+0.497	+3.928	<.001	<.001	3	3
SKCM	FBXL15 →	+0.428	+2.616	.003	<.001	3	3
BLCA	RNU6-598P →	+0.308	+4.376	<.001	.002	3	2
SKCM	P2RX5-TAX1BP3 →	+0.153	+3.534	.006	.002	3	2
SKCM	MIR3115 →	+0.145	+2.593	<.001	.005	3	2
SKCM	ESS2 →	+0.291	+3.195	.009	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,457 associations by consensus.

HMG20B by TEKT5 expression — UCEC

Explore this box plot interactively →