TEKT5

Across TCGA cell cohorts, TEKT5 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEKT5-associated genes across cancer lineages are GHRHR, NTSR2, and REG1B. Each is linked with TEKT5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEKT5-to-partner and partner-to-TEKT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GHRHR grouped by TEKT5-low versus TEKT5-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT5→partner) and Y-score (partner→TEKT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GHRHR →	+0.067	+4.054	<.001	.004	3	1
LARGE_INTESTINE	NTSR2 →	+0.087	+3.793	<.001	.007	3	1
LARGE_INTESTINE	REG1B →	+2.745	+4.196	<.001	.002	3	1
LARGE_INTESTINE	OR10W1 →	+0.015	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	OR10Q1 →	+0.138	+3.920	<.001	.005	3	1
LARGE_INTESTINE	OR52H1 →	+0.033	+4.347	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GHRHR by TEKT5 expression — LARGE_INTESTINE

Explore this box plot interactively →