TEKT4

Across TCGA patient cohorts, TEKT4 mutation is significantly associated with the RNA expression of many other genes, with 859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEKT4-associated genes across cancer lineages are MIR603, OR10K1, and SRSF1P1. Each is linked with TEKT4 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEKT4-to-partner and partner-to-TEKT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR603 grouped by TEKT4-low versus TEKT4-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT4→partner) and Y-score (partner→TEKT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR603 →	+0.340	+3.913	<.001	.003	3	3
SCLC	OR10K1 →	+0.161	+5.624	<.001	.003	3	2
CESC	SRSF1P1 →	+0.099	+6.144	<.001	.001	3	2
LUSC	SPTLC1P2 →	+0.237	+2.578	<.001	.007	3	2
LUSC	RPL17P49 →	+0.052	+3.484	.002	.004	3	2
LUSC	MKNK2P1 →	+0.071	+3.236	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 859 associations by consensus.

MIR603 by TEKT4 expression — HNSC

Explore this box plot interactively →