TEKT4

Across TCGA cell cohorts, TEKT4 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TEKT4-associated genes across cancer lineages are ZSWIM2, C1QA, and OR2A14. Each is linked with TEKT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEKT4-to-partner and partner-to-TEKT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZSWIM2 grouped by TEKT4-low versus TEKT4-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT4→partner) and Y-score (partner→TEKT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	ZSWIM2 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1QA →	+0.206	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OR2A14 →	+0.033	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	PRLHR →	+0.010	+5.247	<.001	.001	3	1
BREAST	AVP →	+0.046	+5.781	<.001	.001	3	1
LUNG_SCLC	FGF3 →	+0.124	+5.169	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

ZSWIM2 by TEKT4 expression — BLOOD_Myeloma

Explore this box plot interactively →