TEKT2

Across TCGA cell cohorts, TEKT2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible TEKT2-associated genes across cancer lineages are ANKRD34C and OR2L8. Each is linked with TEKT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEKT2-to-partner and partner-to-TEKT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD34C grouped by TEKT2-low versus TEKT2-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT2→partner) and Y-score (partner→TEKT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ANKRD34C →	+0.062	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR2L8 →	+0.015	+5.266	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ANKRD34C by TEKT2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →