TEKT1

Across TCGA patient cohorts, TEKT1 mutation is significantly associated with the RNA expression of many other genes, with 1,842 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEKT1-associated genes across cancer lineages are ATF4P2, RNU1-14P, and RN7SKP103. Each is linked with TEKT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEKT1-to-partner and partner-to-TEKT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATF4P2 grouped by TEKT1-low versus TEKT1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT1→partner) and Y-score (partner→TEKT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	ATF4P2 →	+0.056	+5.179	.005	.001	3	3
BLCA	RNU1-14P →	+0.396	+5.018	<.001	.004	3	2
BLCA	RN7SKP103 →	+0.157	+5.814	<.001	.001	3	2
UCEC	MED27 →	+0.416	+2.523	<.001	<.001	3	2
UCEC	ENTR1 →	+0.390	+2.431	.001	.001	3	2
UCEC	WDR72 →	+1.004	+2.807	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,842 associations by consensus.

ATF4P2 by TEKT1 expression — READ

Explore this box plot interactively →