TEKT1

Across TCGA cell cohorts, TEKT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 580 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TEKT1-associated GO terms across cancer lineages are Regulation of protein import into nucleus, Negative regulation of interleukin-1 beta production, and Regulation of intracellular protein transport. Each is linked with TEKT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both TEKT1-to-partner and partner-to-TEKT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein import into nucleus grouped by TEKT1-low versus TEKT1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT1→partner) and Y-score (partner→TEKT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of protein import into nucleus →	+0.059	+0.070	.001	.005	3	5
PANCREAS	Negative regulation of interleukin-1 beta production →	+0.087	+0.194	.004	.004	3	4
PANCREAS	Regulation of intracellular protein transport →	+0.065	+0.167	<.001	.009	2	5
PANCREAS	Response to topologically incorrect protein →	+0.064	+0.199	.001	.003	3	4
PANCREAS	Regulation of nucleocytoplasmic transport →	+0.057	+0.123	.003	.006	2	5
PANCREAS	Response to unfolded protein →	+0.090	+0.183	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 580 associations by consensus.

Regulation of protein import into nucleus by TEKT1 expression — LUNG_NSCLC_LUAD

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