TEKT1

Across TCGA cell cohorts, TEKT1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TEKT1-associated genes across cancer lineages are RESP18, TAS2R7, and MC3R. Each is linked with TEKT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEKT1-to-partner and partner-to-TEKT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RESP18 grouped by TEKT1-low versus TEKT1-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEKT1→partner) and Y-score (partner→TEKT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	RESP18 →	+0.038	+5.196	<.001	.005	3	2
SKIN	TAS2R7 →	+0.014	+3.632	.004	.003	3	1
SKIN	MC3R →	+0.127	+3.658	.002	.005	3	1
SKIN	IZUMO1R →	+0.188	+3.556	.001	.007	3	1
SKIN	IFNA17 →	+0.016	+3.345	<.001	.007	3	1
BLOOD_Leukemia	SLC51B →	+0.050	+3.769	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

RESP18 by TEKT1 expression — OVARY

Explore this box plot interactively →