TEK

Across TCGA pan-cancer cohorts, TEK mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TEK data layer compared with 24 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher TEK mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated TEK expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

LUAD, CCRCC, and GBM are the cancer types where TEK mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.945	1.000	.023	11	view →
CCRCC	OS	Median	All	0.957	0.840	.014	5	view →
GBM	OS	Quartile	All	0.721	0.961	.017	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TEK–LUAD (OS)

Open the LUAD breakdown →