TEFM

Across TCGA patient cohorts, TEFM RNA expression is significantly associated with the protein abundance of many other proteins, with 18,729 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TEFM-associated proteins across cancer lineages are DDX46, LIG3, and ZNF830. Each is linked with TEFM in more than 6 cancer types. Because this analysis shows association rather than direction, both TEFM-to-partner and partner-to-TEFM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TEFM versus DDX46 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TEFM→partner) and Y-score (partner→TEFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DDX46 →	+0.222	+0.340	<.001	<.001	3	7
LSCC	LIG3 →	+0.656	+0.763	<.001	<.001	3	7
LSCC	ZNF830 →	+0.362	+0.626	<.001	<.001	3	6
LSCC	TAF15 →	+0.298	+0.543	<.001	<.001	3	6
UCEC	CDC73 →	+0.310	+0.710	<.001	.002	3	6
LSCC	DHX9 →	+0.321	+0.667	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,729 associations by consensus.

TEFM vs DDX46 — GBM

Explore this scatter interactively →