TEFM

Across TCGA patient cohorts, TEFM protein abundance is significantly associated with the protein abundance of many other proteins, with 22,835 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TEFM-associated proteins across cancer lineages are TFB1M, TIMM44, and SUPV3L1. Each is linked with TEFM in more than 7 cancer types. Because this analysis shows association rather than direction, both TEFM-to-partner and partner-to-TEFM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TEFM versus TFB1M in LSCC, with a Pearson correlation of 0.57.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TEFM→partner) and Y-score (partner→TEFM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TFB1M →	+0.431	+0.344	<.001	<.001	3	8
LSCC	TIMM44 →	+0.426	+0.422	<.001	<.001	3	8
LSCC	SUPV3L1 →	+0.417	+0.422	<.001	<.001	3	8
GBM	LARS2 →	+0.399	+0.286	<.001	<.001	3	8
LSCC	LRPPRC →	+0.608	+0.481	<.001	<.001	3	8
COAD	MRPL38 →	+0.319	+0.464	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,835 associations by consensus.

TEFM vs TFB1M — LSCC

Explore this scatter interactively →