Across TCGA pan-cancer cohorts, TEDDM1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TEDDM1 data layer compared with 21 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher TEDDM1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TEDDM1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

SCLC, LUSC, and UCEC are the cancer types where TEDDM1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	II,III,IV	0.192	0.699	.002	18	view →
LUSC	DFS	Median	II,III,IV	0.199	0.748	.006	9	view →
UCEC	DFS	Median	All	1.000	0.623	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: TEDDM1 tumor-vs-normal RNA expression · all TEDDM1 data types