Across TCGA patient cohorts, TEDDM1 mutation is significantly associated with the RNA expression of many other genes, with 643 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEDDM1-associated genes across cancer lineages are KRT127P, MIR511, and MIR4686. Each is linked with TEDDM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEDDM1-to-partner and partner-to-TEDDM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEDDM1→partner) and Y-score (partner→TEDDM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KRT127P →	+0.067	+5.197	<.001	.003	3	2
LUSC	MIR511 →	+0.652	+6.309	<.001	.001	3	2
LUSC	MIR4686 →	+0.714	+5.093	<.001	.008	3	2
UCEC	CWC25 →	+0.499	+3.475	.002	.002	3	1
UCEC	ZNHIT3 →	+0.482	+3.721	.006	<.001	3	1
UCEC	CCL18 →	+1.815	+3.330	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 643 associations by consensus.

Exploration

TEDDM1 survival (RNA) · tumor vs normal (RNA) · all TEDDM1 data types