Across TCGA patient cohorts, TEDDM1 mutation is significantly associated with the total protein of many other genes, with 14 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEDDM1-associated genes across cancer lineages are EGFR, FoxM1, and MEK1. Each is linked with TEDDM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEDDM1-to-partner and partner-to-TEDDM1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEDDM1→partner) and Y-score (partner→TEDDM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.233	-2.321	.003	.035	3	1
UCEC	FoxM1 →	+0.312	+2.321	.016	.035	3	1
UCEC	MEK1 →	+0.400	+2.321	.029	.035	3	1
UCEC	Syk →	+0.485	+2.820	.009	.035	3	1
UCEC	TAZ →	-0.233	-3.169	.001	.018	3	1
UCEC	Tuberin →	+0.341	+2.321	.011	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

TEDDM1 survival (RNA) · tumor vs normal (RNA) · all TEDDM1 data types