Across TCGA patient cohorts, TEDC1 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEDC1-associated genes across cancer lineages are Caspase-7-cleavedD198, p62 Lck ligand, and PKC-a_pS657. Each is linked with TEDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEDC1-to-partner and partner-to-TEDC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEDC1→partner) and Y-score (partner→TEDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.713	+2.827	.021	.035	3	2
UCEC	p62 Lck ligand →	+0.475	+3.009	.005	.019	3	1
UCEC	PKC-a_pS657 →	+0.503	+3.335	.011	.005	3	1
UCEC	PKC-a →	+0.478	+3.321	.024	.010	3	1
UCEC	AMPK_pT172 →	+0.504	+3.169	.019	.019	3	1
UCEC	STAT5a →	+0.426	+3.321	.042	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

TEDC1 survival (RNA) · tumor vs normal (RNA) · all TEDC1 data types