TECTA

Across TCGA patient cohorts, TECTA protein abundance is significantly associated with the RNA expression of many other genes, with 15,080 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TECTA-associated genes across cancer lineages are SLC16A1, AKR7A2P1, and SLC16A1-AS1. Each is linked with TECTA in more than 9 cancer types. Because this analysis shows association rather than direction, both TECTA-to-partner and partner-to-TECTA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TECTA versus SLC16A1 in BRCA, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TECTA→partner) and Y-score (partner→TECTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SLC16A1 →	+1.152	+1.026	<.001	<.001	3	10
HNSC	AKR7A2P1 →	+0.853	+0.800	<.001	<.001	3	7
UCEC	SLC16A1-AS1 →	+1.007	+1.336	<.001	<.001	3	5
HNSC	ZMAT1 →	-0.905	-0.655	<.001	<.001	3	5
BRCA	ARRB1 →	-0.738	-0.908	.001	<.001	3	5
HNSC	DOK5 →	-0.829	-0.719	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,080 associations by consensus.

TECTA vs SLC16A1 — BRCA

Explore this scatter interactively →