TECTA

Across TCGA cell cohorts, TECTA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,428 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TECTA-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Epigenetic regulation of gene expression, and Regulation of myoblast fusion. Each is linked with TECTA in more than 14 cancer types. Because this analysis shows association rather than direction, both TECTA-to-partner and partner-to-TECTA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by TECTA-low versus TECTA-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TECTA→partner) and Y-score (partner→TECTA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.089	+0.197	<.001	.002	3	15
LIVER	Epigenetic regulation of gene expression →	+0.062	+0.375	<.001	.006	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.074	+0.129	<.001	.002	3	14
SKIN	Negative regulation of myoblast fusion →	+0.086	+0.249	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of translational initiation →	+0.093	+0.192	<.001	.007	3	13
SOFT_TISSUE	Cytoplasmic translation →	+0.065	+0.494	.001	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,428 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by TECTA expression — KIDNEY

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