TECRL

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TECRL mutation is significantly associated with the total protein of many other genes, with 61 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TECRL-associated genes across cancer lineages are Caspase-7-cleavedD198, Chk2, and GSK3-a-b. Each is linked with TECRL in more than 2 cancer types. Because this analysis shows association rather than direction, both TECRL-to-partner and partner-to-TECRL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TECRL→partner) and Y-score (partner→TECRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCaspase-7-cleavedD198 →+1.111+3.016.001.01833
LUSCChk2 →+0.325+2.594.004.00632
LUSCGSK3-a-b →+0.159+2.825.030.03332
UCEC14-3-3_beta →-0.091-1.349.010.03732
UCECEGFR_pY1068 →-0.204-1.362.021.03732
UCECeIF4E →+0.151+2.820.043.03532
Each partner links to its Q-omics profile. Showing the 6 strongest of 61 associations by consensus.

Exploration