Across TCGA cell cohorts, TECRL mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TECRL-associated genes across cancer lineages are USP17L7, PRORY, and MSGN1. Each is linked with TECRL in more than 1 cancer types. Because this analysis shows association rather than direction, both TECRL-to-partner and partner-to-TECRL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TECRL→partner) and Y-score (partner→TECRL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	USP17L7 →	+0.054	+3.333	.001	.009	3	2
SKIN	PRORY →	+0.641	+4.273	.002	.006	3	1
LARGE_INTESTINE	MSGN1 →	+0.080	+3.760	<.001	<.001	3	1
LARGE_INTESTINE	COL6A5 →	+0.540	+3.724	<.001	.004	3	1
LARGE_INTESTINE	FAM153B →	+0.577	+3.618	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.241	+4.009	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

TECRL survival (RNA) · tumor vs normal (RNA) · all TECRL data types