Across TCGA patient cohorts, TECPR2 mutation is significantly associated with the total protein of many other genes, with 77 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TECPR2-associated genes across cancer lineages are PAI-1, ATM, and NF-kB-p65_pS536. Each is linked with TECPR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both TECPR2-to-partner and partner-to-TECPR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TECPR2→partner) and Y-score (partner→TECPR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PAI-1 →	+1.040	+2.476	<.001	.009	3	4
UCEC	ATM →	-0.483	-1.628	<.001	<.001	3	4
COAD	NF-kB-p65_pS536 →	-0.563	-3.000	.011	.034	3	3
COAD	Cyclin-D1 →	+0.138	+3.016	.011	.018	3	3
UCEC	TFRC →	+0.465	+3.247	.001	<.001	3	3
SKCM	B-Raf →	-0.408	-2.459	.004	.018	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 77 associations by consensus.

Exploration

TECPR2 survival (RNA) · tumor vs normal (RNA) · all TECPR2 data types