TECPR1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TECPR1 mutation is significantly associated with the RNA expression of many other genes, with 2,803 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TECPR1-associated genes across cancer lineages are MYRF-AS1, PRSS23, and ZWILCH. Each is linked with TECPR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TECPR1-to-partner and partner-to-TECPR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TECPR1→partner) and Y-score (partner→TECPR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMYRF-AS1 →+0.076+1.507<.001.00233
COADPRSS23 →-0.891-2.893<.001.00133
UCECZWILCH →+0.425+2.234<.001<.00133
UCECSPAG5 →+0.470+2.066.001<.00133
UCECKHSRP →+0.287+1.803.005<.00133
UCECFCER1A →-0.793-2.402<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,803 associations by consensus.

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