Across TCGA patient cohorts, TEAD4 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,188 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible TEAD4-associated proteins across cancer lineages are WDR75, NOP2, and NOL11. Each is linked with TEAD4 in more than 6 cancer types. Because this analysis shows association rather than direction, both TEAD4-to-partner and partner-to-TEAD4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD4→partner) and Y-score (partner→TEAD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WDR75 →	+0.342	+0.814	<.001	.001	3	7
BRCA	NOP2 →	+0.637	+0.994	<.001	.001	3	7
LSCC	NOL11 →	+0.398	+0.816	<.001	<.001	3	7
PDAC	NCAPD2 →	+0.602	+0.462	<.001	<.001	3	7
UCEC	WDR43 →	+0.387	+0.766	<.001	<.001	3	7
LUAD	DDX21 →	+0.522	+0.771	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,188 associations by consensus.

Exploration

TEAD4 survival (RNA) · tumor vs normal (RNA) · all TEAD4 data types