Across TCGA cell cohorts, TEAD4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,241 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TEAD4-associated GO terms across cancer lineages are DNA replication initiation, Mitotic spindle elongation, and Mitotic spindle midzone assembly. Each is linked with TEAD4 in more than 14 cancer types. Because this analysis shows association rather than direction, both TEAD4-to-partner and partner-to-TEAD4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD4→partner) and Y-score (partner→TEAD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.168	+1.351	<.001	<.001	3	15
SOFT_TISSUE	Mitotic spindle elongation →	+0.222	+1.217	.002	.002	3	14
SOFT_TISSUE	Mitotic spindle midzone assembly →	+0.222	+1.217	.002	.002	3	14
BONE	Nucleolar large rRNA transcription by RNA polymerase I →	+0.130	+0.873	<.001	.006	3	13
PANCREAS	Spindle elongation →	+0.216	+1.033	<.001	<.001	3	13
BONE	Double-strand break repair via break-induced replication →	+0.222	+1.104	.002	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,241 associations by consensus.

Exploration

TEAD4 survival (RNA) · tumor vs normal (RNA) · all TEAD4 data types