Across TCGA cell cohorts, TEAD4 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEAD4-associated genes across cancer lineages are FTMT, POTEB2, and TAAR6. Each is linked with TEAD4 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEAD4-to-partner and partner-to-TEAD4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD4→partner) and Y-score (partner→TEAD4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FTMT →	+0.139	+5.029	<.001	.006	3	1
LUNG_SCLC	POTEB2 →	+0.019	+5.029	<.001	.006	3	1
LARGE_INTESTINE	TAAR6 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	MRAP →	+0.022	+3.345	<.001	.007	3	1
LARGE_INTESTINE	ELOA3DP →	+0.025	+3.688	<.001	.002	3	1
LARGE_INTESTINE	KIR2DS4 →	+0.009	+4.345	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

TEAD4 survival (RNA) · tumor vs normal (RNA) · all TEAD4 data types