TEAD3

Across TCGA patient cohorts, TEAD3 mutation is significantly associated with the RNA expression of many other genes, with 609 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEAD3-associated genes across cancer lineages are MLLT10P2, RNU6-796P, and LINC01784. Each is linked with TEAD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEAD3-to-partner and partner-to-TEAD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MLLT10P2 grouped by TEAD3-low versus TEAD3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD3→partner) and Y-score (partner→TEAD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MLLT10P2 →	+0.073	+4.469	<.001	.006	3	2
BLCA	RNU6-796P →	+0.597	+4.266	<.001	.003	3	2
SKCM	LINC01784 →	+0.065	+6.816	<.001	<.001	3	2
UCEC	SLCO1B3 →	+0.664	+2.285	<.001	.008	3	2
CESC	DEFB123 →	+0.119	+5.010	<.001	.009	3	1
CESC	MIR920 →	+0.583	+5.539	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 609 associations by consensus.

MLLT10P2 by TEAD3 expression — SKCM

Explore this box plot interactively →