Across TCGA patient cohorts, TEAD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,424 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TEAD1-associated proteins across cancer lineages are ANTXR1, SEC11C, and SPCS3. Each is linked with TEAD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TEAD1-to-partner and partner-to-TEAD1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD1→partner) and Y-score (partner→TEAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ANTXR1 →	+0.550	+0.575	<.001	.001	3	6
LUAD	SEC11C →	-0.757	-0.382	.001	<.001	3	5
LUAD	SPCS3 →	-0.497	-0.461	.001	<.001	3	5
CCRCC	CD38 →	-0.699	-0.435	<.001	<.001	3	5
LSCC	EVI2B →	-0.540	-0.490	<.001	<.001	3	5
CCRCC	ITGAL →	-0.544	-0.381	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,424 associations by consensus.

Exploration

TEAD1 survival (RNA) · tumor vs normal (RNA) · all TEAD1 data types