Across TCGA patient cohorts, TEAD1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,637 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TEAD1-associated genes across cancer lineages are RBFOX2, ASPN, and BACH2. Each is linked with TEAD1 in more than 5 cancer types. Because this analysis shows association rather than direction, both TEAD1-to-partner and partner-to-TEAD1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD1→partner) and Y-score (partner→TEAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBFOX2 →	+0.614	+0.488	<.001	<.001	3	6
BRCA	ASPN →	+1.883	+0.518	<.001	<.001	3	5
UCEC	BACH2 →	+0.817	+0.504	<.001	<.001	3	5
BRCA	TGFB1I1 →	+0.864	+0.507	.003	.004	3	5
BRCA	FILIP1L →	+1.082	+0.617	<.001	<.001	3	5
UCEC	BNC2 →	+1.284	+0.477	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,637 associations by consensus.

Exploration

TEAD1 survival (RNA) · tumor vs normal (RNA) · all TEAD1 data types