Across TCGA patient cohorts, TEAD1 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TEAD1-associated genes across cancer lineages are ASNS, Ku80, and S6_pS240_S244. Each is linked with TEAD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TEAD1-to-partner and partner-to-TEAD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD1→partner) and Y-score (partner→TEAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.351	+2.070	.001	.001	3	3
UCEC	Ku80 →	+0.266	+2.335	<.001	<.001	3	2
UCEC	S6_pS240_S244 →	+0.335	+1.643	.007	.003	3	2
UCEC	S6 →	+0.222	+2.000	.007	.029	3	2
UCEC	STAT3_pY705 →	-0.290	-1.415	<.001	.010	3	2
UCEC	Caspase-7-cleavedD198 →	+0.558	+1.682	.002	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Exploration

TEAD1 survival (RNA) · tumor vs normal (RNA) · all TEAD1 data types