Across TCGA cell cohorts, TEAD1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TEAD1-associated genes across cancer lineages are DYNAP, GABRG1, and FAM205A. Each is linked with TEAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TEAD1-to-partner and partner-to-TEAD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TEAD1→partner) and Y-score (partner→TEAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DYNAP →	+0.071	+4.867	.002	.009	3	1
LARGE_INTESTINE	GABRG1 →	+0.009	+3.196	.001	.007	3	1
LARGE_INTESTINE	FAM205A →	+0.020	+3.614	<.001	.006	3	1
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
BLOOD_Leukemia	FAM71B →	+0.024	+5.060	<.001	.001	3	1
BLOOD_Leukemia	OR10T2 →	+1.072	+4.276	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

TEAD1 survival (RNA) · tumor vs normal (RNA) · all TEAD1 data types