Across TCGA patient cohorts, TDRG1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TDRG1-associated genes across cancer lineages are RNU6-228P, RNU6-933P, and MIR1285-2. Each is linked with TDRG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TDRG1-to-partner and partner-to-TDRG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRG1→partner) and Y-score (partner→TDRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-228P →	+0.639	+3.863	<.001	.002	3	1
UCEC	RNU6-933P →	+0.610	+4.506	.004	<.001	3	1
UCEC	MIR1285-2 →	+0.453	+3.638	.004	.006	3	1
UCEC	RNA5SP146 →	+0.468	+3.525	<.001	.008	3	1
UCEC	GOLGA6L11P →	+0.037	+4.877	<.001	.003	3	1
UCEC	MORF4L1P7 →	+0.099	+4.877	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

TDRG1 survival (RNA) · tumor vs normal (RNA) · all TDRG1 data types