TDRD9

Across TCGA cell cohorts, TDRD9 RNA expression is significantly associated with the go_rna of many other GO terms, with 710 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TDRD9-associated GO terms across cancer lineages are Transposable element silencing by piRNA-mediated heterochromatin formation, Heart valve morphogenesis, and Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator. Each is linked with TDRD9 in more than 3 cancer types. Because this analysis shows association rather than direction, both TDRD9-to-partner and partner-to-TDRD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transposable element silencing by piRNA-mediated heterochromatin formation grouped by TDRD9-low versus TDRD9-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD9→partner) and Y-score (partner→TDRD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Transposable element silencing by piRNA-mediated heterochromatin formation →	+1.129	+2.177	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Heart valve morphogenesis →	-0.048	-1.055	.004	.002	3	3
CNS	Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator →	+0.052	+0.370	<.001	.008	3	3
CNS	Positive regulation of telomere maintenance via telomerase →	+0.046	+0.384	<.001	.005	3	3
BLOOD_Leukemia	Regulation of stem cell division →	-0.111	-1.208	<.001	.002	3	3
BLOOD_Lymphoma	Primary heart field specification →	-0.664	-1.163	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 710 associations by consensus.

Transposable element silencing by piRNA-mediated heterochromatin formation by TDRD9 expression — BLOOD_Lymphoma

Explore this box plot interactively →