TDRD9

Across TCGA cell cohorts, TDRD9 mutation is significantly associated with the RNA expression of many other genes, with 627 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TDRD9-associated genes across cancer lineages are CLLU1-AS1, DYNAP, and AADACL2. Each is linked with TDRD9 in more than 2 cancer types. Because this analysis shows association rather than direction, both TDRD9-to-partner and partner-to-TDRD9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLLU1-AS1 grouped by TDRD9-low versus TDRD9-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD9→partner) and Y-score (partner→TDRD9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CLLU1-AS1 →	+0.827	+3.341	.004	.009	2	3
BLOOD_Lymphoma	DYNAP →	+0.042	+3.452	.008	.004	3	2
BLOOD_Lymphoma	AADACL2 →	+0.008	+3.925	<.001	.006	3	2
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	2
SKIN	GALP →	+0.017	+4.415	<.001	.007	3	2
LARGE_INTESTINE	DRG2 →	+0.412	+2.588	.009	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 627 associations by consensus.

CLLU1-AS1 by TDRD9 expression — BLOOD_Lymphoma

Explore this box plot interactively →