Across TCGA patient cohorts, TDRD7 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TDRD7-associated genes across cancer lineages are eEF2, eIF4E, and ASNS. Each is linked with TDRD7 in more than 2 cancer types. Because this analysis shows association rather than direction, both TDRD7-to-partner and partner-to-TDRD7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD7→partner) and Y-score (partner→TDRD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eEF2 →	+0.348	+3.178	.016	.010	3	3
UCEC	eIF4E →	+0.207	+3.169	.001	<.001	3	3
UCEC	ASNS →	+0.316	+1.440	.004	.022	3	3
UCEC	Caspase-7-cleavedD198 →	+0.457	+1.945	.013	.002	3	3
COAD	PCNA →	+0.315	+3.178	.009	.010	3	2
COAD	Rab25 →	-0.264	-3.161	.041	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

TDRD7 survival (RNA) · tumor vs normal (RNA) · all TDRD7 data types