Across TCGA cell cohorts, TDRD7 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible TDRD7-associated genes across cancer lineages are FAM205A, MS4A10, and SULT1C3. Each is linked with TDRD7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TDRD7-to-partner and partner-to-TDRD7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD7→partner) and Y-score (partner→TDRD7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM205A →	+0.031	+4.029	<.001	<.001	3	1
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
OVARY	SULT1C3 →	+0.192	+5.196	<.001	.005	3	1
BLOOD_Lymphoma	UGT2B10 →	+0.011	+4.714	<.001	.002	3	1
BLOOD_Lymphoma	CCL15 →	+0.099	+4.714	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

TDRD7 survival (RNA) · tumor vs normal (RNA) · all TDRD7 data types