TDRD6

Across TCGA cell cohorts, TDRD6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,228 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TDRD6-associated GO terms across cancer lineages are Cholesterol catabolic process, Sterol catabolic process, and Adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Each is linked with TDRD6 in more than 13 cancer types. Because this analysis shows association rather than direction, both TDRD6-to-partner and partner-to-TDRD6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cholesterol catabolic process grouped by TDRD6-low versus TDRD6-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD6→partner) and Y-score (partner→TDRD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Cholesterol catabolic process →	-0.351	-0.150	<.001	<.001	3	14
OESOPHAGUS	Sterol catabolic process →	-0.351	-0.150	<.001	<.001	3	14
LUNG_NSCLC_LUAD	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.026	-0.109	.001	.009	3	10
PANCREAS	Regulation of syncytium formation by plasma membrane fusion →	+0.096	+0.112	<.001	.005	2	9
OVARY	Regulation of myoblast fusion →	+0.114	+0.241	<.001	.001	3	8
OVARY	Negative regulation of syncytium formation by plasma membrane fusion →	+0.114	+0.212	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,228 associations by consensus.

Cholesterol catabolic process by TDRD6 expression — OESOPHAGUS

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