TDRD5

Across TCGA patient cohorts, TDRD5 protein abundance is significantly associated with the RNA expression of many other genes, with 527 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible TDRD5-associated genes across cancer lineages are BRD1, POLA1, and PRPS2. Each is linked with TDRD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TDRD5-to-partner and partner-to-TDRD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TDRD5 versus BRD1 in HNSC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD5→partner) and Y-score (partner→TDRD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	BRD1 →	-0.482	-1.257	.006	.009	3	1
HNSC	POLA1 →	+0.805	+1.441	.005	.002	3	1
HNSC	PRPS2 →	+0.926	+1.560	.009	<.001	3	1
HNSC	MGRN1 →	-0.780	-1.915	.002	.001	3	1
HNSC	MEFV →	+0.991	+1.756	.001	<.001	3	1
HNSC	AQP9 →	+1.448	+1.456	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

TDRD5 vs BRD1 — HNSC

Explore this scatter interactively →