TDRD5

Across TCGA cell cohorts, TDRD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,107 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible TDRD5-associated GO terms across cancer lineages are Post-transcriptional gene silencing, Establishment of vesicle localization, and Cytoplasmic translation. Each is linked with TDRD5 in more than 7 cancer types. Because this analysis shows association rather than direction, both TDRD5-to-partner and partner-to-TDRD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Post-transcriptional gene silencing grouped by TDRD5-low versus TDRD5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TDRD5→partner) and Y-score (partner→TDRD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Post-transcriptional gene silencing →	+0.060	+1.547	<.001	.002	3	8
BREAST	Establishment of vesicle localization →	+0.041	+0.906	<.001	.008	3	6
SKIN	Cytoplasmic translation →	+0.048	+0.177	.005	.008	3	6
OVARY	Cytoplasmic translational initiation →	+0.064	+0.390	<.001	.002	3	6
SKIN	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.043	-0.187	<.001	.007	3	6
BLOOD_Myeloma	Regulatory ncRNA-mediated post-transcriptional gene silencing →	+0.050	+0.846	<.001	.008	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,107 associations by consensus.

Post-transcriptional gene silencing by TDRD5 expression — BLOOD_Myeloma

Explore this box plot interactively →